Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Endocrinol Metab and Elmer Press Inc |
Journal website http://www.jofem.org |
Original Article
Volume 5, Number 6, December 2015, pages 333-336
Observational Study of the Use of Insulin Glargine as Basal Therapy in Patients With Type 2 Diabetes Mellitus in Morocco
Tables
Characteristic | |
---|---|
All values shown are n (%), or mean ± SD. | |
Sex | |
Male/female | 220/274 (44.5/55.5) |
Age (years) | 57.5 ± 10.3 |
Age group (years) | |
18 - 40 | 15 (3.1) |
41 - 50 | 98 (20.0) |
51 - 60 | 185 (37.7) |
61 - 70 | 133 (27.1) |
> 70 | 60 (12.2) |
Duration of diabetes (years) | 9.8 ± 6.1 |
Body mass index | |
< 25 kg/m2 | 118 (25.3) |
25 - 30 kg/m2 | 230 (49.1) |
> 30 kg/m2 | 120 (25.6) |
Insulin therapy | |
Initiation of insulin glargine | 388 (78.1) |
Modification of insulin (change to insulin glargine) | 109 (21.9) |
Week 12 (visit 2) | Week 26 (visit 3) | |
---|---|---|
Results are shown as n (%). OAD: antidiabetic drugs. | ||
Total number of OAD changes | 150/477 (31.4) | 57/454 (12.6) |
OAD stopped | 98/477 (20.5) | 37/454 (8.1) |
OAD added | 87/477 (18.2) | 31/442 (7.0) |
Sulphonylureas stopped | 48/477 (10.1) | 16/454 (3.5) |
Biguanides stopped | 28/477 (5.9) | 16/454 (3.5) |
Insulin glargine | ||
Dose changed | 398/484 (82.2) | 225/470 (47.9) |
Rapid insulin added | 45/484 (9.3) | 33/470 (7.0) |
Inclusion | Week 12 | Week 26 | P | ||
---|---|---|---|---|---|
I-W12 | I-W26 | ||||
Values shown are n (%), or mean ± SD. FBG: fasting blood glucose. | |||||
HbA1c ≤ 7% | 0 (0) | 55 (11.5) | 149 (32.0) | ||
HbA1c (%) | 9.37±1.14 | 8.08±1.03 | 7.43±0.87 | < 0.001 | < 0.001 |
FBG (mg/dL) | 237.5 ± 66.9 | 154.4 ± 47.7 | 129.5 ± 35.1 | < 0.001 | < 0.001 |