Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access
Article copyright, the authors; Journal compilation copyright, J Endocrinol Metab and Elmer Press Inc
Journal website http://www.jofem.org

Case Report

Volume 6, Number 1, February 2016, pages 23-26

Ulcerative Colitis and Grave’s Disease: Is There Any Relationship?

Figure

Figure 1.
Figure 1. Tc-99m pertechnetate thyroid scintigraphy showing a homogenously increased activity in a moderately enlarged thyroid.

Tables

Table 1. Extra-Intestinal Manifestations of IBD
 
Extra-intestinal manifestationDiseases
Musculoskeletal systemPeripheral arthritis, ankylosing spondylitis, isolated sacroiliitis
Mucocutaneous systemErythema nodosum, pyoderma gangrenosum, aphthous stomatitis/oral ulceration
EyeAnterior uveitis, conjunctivitis, iritis, scleritis/episcleritis
Hepatobiliary systemPrimary sclerosing cholangitis
PancreasAcute pancreatitis, chronic pancreatitis, exocrine insufficiency
Vascular systemThromboembolic events
KidneyTubular proteinuria
Bronchopulmonary systemChronic bronchitis/bronchiolitis/bronchiectasis, acute laryngotracheitis/tracheal stenosis - bronchiolitis obliterans organizing pneumonia, pleuritis/serositis
HeartPericarditis, myocarditis
Neurological systemDemyelinating diseases including multiple sclerosis, optic neuritis, sensorial hearing loss

 

Table 2. Reported Cases of UC and Autoimmune Thyroiditis Association
 
AuthorsAgeSexNature of autoimmune thyroid diseaseOrder of occurrenceOther associated autoimmune disease
Powell et al [4]34FemaleGrave’s diseaseSimultaneousAddison’s disease
Jarnerot et al [3]73FemaleGrave’s diseaseSimultaneous-
Triantafillidis et al [7]42MaleGrave’s diseaseSimultaneous-
Eugene et al [6]41FemaleGrave’s diseaseSimultaneous-
Modebe [8]41FemaleGrave’s diseaseGrave’s disease first-
32FemaleGrave’s diseaseGrave’s disease first-
Baldys-Waligorska et al [9]45FemaleHashimoto thyroiditisHashimoto thyroiditis firstArthritis
Topal et al [10]46FemaleHashimoto thyroiditisHashimoto thyroiditis firstVitiligo
Nishimura et al [11]26FemaleGrave’s diseaseUlcerative colitis first-
Oshitani et al [12]61FemaleGrave’s diseaseUlcerative colitis firstDermatomyositis, multiple mononeuritis
Ito et al [13]46MaleGrave’s diseaseGrave’s disease first-
Chiba et al [14]66FemaleGrave’s diseaseUlcerative colitis first-
Hasegawa et al [15]41FemaleGrave’s diseaseSimultaneous-
Nakamura et al [11]50MaleGrave’s diseaseGrave’s disease first-
Okai et al [16]30FemaleGrave’s diseaseGrave’s disease first-
Lyer et al [17]46FemaleGrave’s diseaseGrave’s disease first-
18MaleGrave’s diseaseGrave’s disease first-
Najafi et al [18]20MaleHashimoto thyroiditisSimultaneousType 1 diabetes, autoimmune hepatitis