Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Endocrinol Metab and Elmer Press Inc |
Journal website http://www.jofem.org |
Original Article
Volume 8, Number 1, February 2018, pages 2-5
Evaluation of Bone Turnover in Patients With Type 1 Diabetes Mellitus
Tables
Md (Q1/Q3) | T1DM n = 98 | Non-DM controls n = 82 | ||
---|---|---|---|---|
M: male; F: female. | ||||
Sex (M:F) | M : 41 | F : 57 | M : 39 | F : 43 |
Age (years) | 56 (51/61) | 58 (52/63) | 58 (51/64) | 56 (49/60) |
Duration of DM (years) | 15 (11/20) | 18 (12/22) | NA | NA |
BMI (kg/m2 ) | 25 (25/27) | 26(24/27) | 28(25/30) | 28 (26/32) |
FPG (mmol/L) | 7.9 (6.7/9.7) | 6.6 (5.9/8.0) | 4.9 (4.5/5.1) | 5.0 (4.7/5.2) |
HbA1C (%) | 7.2 (6.5/8.1) | 7.4 (6.3/8.8) | 5.0 (4.7/5.2) | 5.0 (4.8/5.1) |
Ca2+ | 1.17 (1.11/1.19) | 1.06 (0.98/1.12) | 1.19 (1.14/1.2) | 1.11(1.07/1.14) |
Inorganic P | 5.6 (5.1/6.2) | 5.3 (4.9/5.9) | 5.2 (4.8/5.4) | 5.0 (4.6/5.4) |
Mg2+ | 1.8 (1.3/2.2) | 1.3 (1.1/1.7) | 1.8 (1.7/2.2) | 1.6 (1.2/1.9) |
Creatinine (mg/dL) | 0.9 (0.7/1.05) | 0.8 (0.72/0.86) | 0.7 (0.62/0.91) | 0.7 (0.66/0.82) |
eGFR (mL/min/1.73 m2) | 93 (75/103.5) | 82 (73/93.5) | 104 (88.5/110) | 93 (77/102.5) |
Total cholesterol (mg/dL) | 185 (165/216) | 198 (157/229) | 163 (157/192) | 168 (158/206) |
Md (Q1/Q3) % | T1DM n = 98 | Non-DM controls n = 82 | ||
---|---|---|---|---|
*P < 0.05, **P < 0.005, ***P < 0.001 compared with patients of the control group; "P < 0.05, ""P < 0.005, """P < 0.001 compared with female patients of the same group. | ||||
Sex (M:F) | M : 41 | F:57 | M : 39 | F : 43 |
ALP ( IU/L) | 117.1" (101.4/146.8) | 102.2 (89.6/138.1) | 134.1" (95.9/152.1) | 105.1 (87.8/133.8) |
P1NP (ng/mL) | 41.31"" (33.22/49.06) | 33.16*** (28.16/41.50) | 45.95 (30.20/59.44) | 47.99 (36.98/60.77) |
b-CTх (ng/mL) | 0.412* (0.328/0.557) | 0.508 (0.368/0.648) | 0.338"" (0.261/0.45) | 0.442 (0.350/0.533) |
Spine Т-score (L1-L4) | -1.4***"" (-2.2/-0.9) | -2.4** (-3.0/-1.5) | -0.1""" (-0.6/0.7) | -1.0 (-2.1/-0.4) |
22 (54%) | 41 (72%) | 5 (13%) | 16 (37%) | |
Proximal femur Т-score | -0.7*"" (-1.4/-0.2) | -2.1*** (-2.4/-1.4) | -0.1 (-0.7/0.8) | -0.7 (-1.6/0.2) |
11 (27%) | 24 (42%) | 4 (10%) | 13 (30%) | |
Femoral neck T-score | -1.15**" (-1.9/-0.7) | -2.3** (-2.7/-1.3) | -0.0 (-1.0/0.6) | -0.85 (-1.9/0.3) |
17 (41%) | 23 (40%) | 6 (15%) | 15 (30%) | |
Spine Z-score (L1-L4) | -0.75*** (-1.8/0.07) | -0.9** (-2.1/-0.3) | 1.1"" (0.3/1.4) | -0.1 (-0.7/0.8) |
12 (29%) | 21 (37%) | 3 (8%) | 6 (14%) | |
Proximal femur Z-score | -0.15" (-0.9/0.5) | -1.2*** (-1.4/-0.4) | 0.4 (0.0/1.2) | -0.05 (-0.7/0.8) |
6 (15%) | 16 (28%) | 3 (8%) | 7 16(%) | |
Femoral neck Z-score | -0.1*" (-0.8/0.4) | -1.0* (-1.4/-0.1) | 0.4 (-0.1/1.5) | -0.05 (-0.7/1.1) |
5 (12%) | 15 (26%) | 2 (5%) | 6 (14%) |
% | T1DM n = 98 | Non-DM controls n = 82 | ||
---|---|---|---|---|
Sex (M : F) | M : 41 | F : 57 | M : 39 | F : 43 |
L1 - L2 | 7 (17%) | 10 (17.5 %) | 1 (2.5%) | 5 (12%) |
L3 - L4 | 15 (36.5%) | 31 (54%) | 4 (10%) | 11 (25.5%) |
Left hip | 10 (24%) | 13 (23%) | 5 (13%) | 9 (21%) |
Right hip | 7 (17%) | 10 (17.5%) | 1 (2.5%) | 6 (14%) |