Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access
Article copyright, the authors; Journal compilation copyright, J Endocrinol Metab and Elmer Press Inc
Journal website http://www.jofem.org

Case Report

Volume 8, Number 1, February 2018, pages 6-9


Improved Glycemic Control due to Reduction in Glucagon Levels by the Administration of Once-Weekly Dulaglutide in a Non-Obese Patient With Type 2 Diabetes

Figure

Figure 1.
Figure 1. Daily plasma glucose profile as well as fasting and 2-h postprandial levels of C-peptide and glucagon before the administration of once-weekly dulaglutide (a) and after switching from vildagliptin to dulaglutide (b).

Table

Table 1. Characteristics of the Patient
 
BMI: body mass index; WC: waist circumference; AST: aspartate aminotransferase; ALT: alanine aminotransferase; BUN: blood urea nitrogen; Cre: creatinine; eGFR: estimated glomerular filtration rate; HbA1c: hemoglobin A1c; GA: glycoalbumin; U-ACR: urinary albumin creatinine ratio.
Age (years)67
Height (cm)156.2
Weight (kg)50
BMI (kg/m2)20.5
WC (cm)82.5
Duration of diabetes (years)15
AST (U/L)55
ALT (U/L)60
BUN (mg/dL)7.3
Cre (mg/dL)0.48
eGFR (ml/min/1.73 m2)95.7
Plasma glucose (mg/dL)206
HbA1c (%)11.1
GA (%)29.6
U-ACR (mg/gCre)0