Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access
Article copyright, the authors; Journal compilation copyright, J Endocrinol Metab and Elmer Press Inc
Journal website http://www.jofem.org

Original Article

Volume 2, Number 4-5, October 2012, pages 171-175

Anemia in Spontaneously Type 2 Diabetic Rats With Renal Impairment

Figures

Figure 1.
Figure 1. Blood smear of a 12-month old eSS diabetic showing polychromasia, a Howell-Jolly body (center) and Rouleaux formation. May-Grünwald-Giemsa stain. 100 ×.
Figure 2.
Figure 2. Blood smear of a 12-month eSS diabetic showing an erythroblast (center). May-Grünwald-Giemsa stain. 100 ×.
Figure 3.
Figure 3. Mild diffuse mesangial thickening of the glomerular basement membrane (12-month old eSS male). HE and Periodic acid-Schiff (PAS) stain. 300×.
Figure 4.
Figure 4. Moderate tubular dilatation with atrophic epithelium, containing proteinaceous cylinders. HE stain. 100 ×.

Table

Table 1. Body Weight (Bw), Fasting Glycemia (G0), Fructosamine (FH2), Red Blood Cell Count (RBC), Hemoglobin Concentration (Hb), Hematocrit (Ht), Mean Cell Volume (MCV), Mean Cell Hemoglobin (MCH) and Mean Cell Hemoglobin Concentration (MCHC) in Diabetic eSS Rats and in Euglycemic Wistar Rats
 
RatsBw (g)G0 (mg/dL)FH2 (µmol/L)RBC (×106/ mm3)Hb (g/dL)Ht (%)VMC (fl)MCH (pg)MCHC (g/dL)
Values expressed as mean ± standard deviation; fl: femtoliters.
eSS (n =12)415±21147 ± 15182 ± 176.39 ±0.1611.09± 0.2234 ±0.8449.3±1.117.2±0.1734.9 ±0.29
Wistar (n =11)410±36103 ± 10121 ± 147.88 ±0.0713.9 ±0.1339 ±0.4148 ±0.2216.5±0.0634.3 ±0.09
P>0.05< 0.001< 0.001< 0.001<0.001<0.001>0.05<0.01> 0.05