Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access
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Case Report

Volume 1, Number 3, August 2011, pages 142-145

Myelofibrosis and Antiphospholipid Syndrome Presenting With Adrenal Insufficiency Due to Bilateral Adrenal Hemorrhage: A Case Series


Figure 1.
Figure 1. CT scan of the abdomen of a 59-year-old female patient with myelofibrosis showing evidence of enlarged bilateral adrenal hemorrhage (arrows) (a). CT scan of the abdomen of the same patient four months previously showing splenomegaly and normal left adrenal (arrow), theright adrenal is barely visible between the liver and right diaphragmatic crus (b), and 7 months after admission showing reduction in the size of both adrenal glands (only the left adrenal gland as indicated by arrow is visible in this image) compared to the previous examination (Fig. 1a) consistent with resolving hemorrhage (c).
Figure 2.
Figure 2. CT scan of the abdomen of an 84-year-old male patient with APS showing evidence of bilateral adrenal hemorrhage.
Figure 3.
Figure 3. Possible mechanisms leading to organ hemorrhage in patients with myelofibrosis treated with antiplatelet or anticoagulant medications (dashed lines indicate potentiation effect).