Figure 1. The protocol of this study.
| Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Endocrinol Metab and Elmer Press Inc |
| Journal website http://www.jofem.org |
Original Article
Volume 7, Number 1, February 2017, pages 25-30
Evaluation of the Efficacy of Potassium Iodide Preparation for Radioactive Iodine Therapy in Graves’ Disease: A Retrospective Chart Review
Figure
Tables
| KI | MMI | P-value | |
|---|---|---|---|
| Age (mean ± SD) | 41.9 ± 11.4 | 39.2 ± 13.6 | n.s. |
| Gender (male/female) | 2:9 | 0:13 | n.s. |
| Smoking (yes/no) | 3:8 | 2:11 | n.s. |
| Duration of GD treatment (median (25-75%)), months | 16.0 (3.0 - 52.0) | 37.0 (16.5 - 58.5) | n.s. |
| FT4 before discontinuation of KI or MMI (median (25-75%)), ng/dL | 2.11 (1.58 - 2.48) | 1.21 (1.00 - 1.49) | P < 0.05 |
| Method of RAIT (fixed dose/calculated dose) | 8:3 | 3:10 | P < 0.05 |
| Dose of drugs before RAIT, (median (25-75%)), mg | - | ||
| MMI (n = 0:13) | - | 12.5 (7.5 - 16.3) | |
| KI (n = 11:0) | 150 (100 - 200) | - |
| KI | MMI | P-value | |
|---|---|---|---|
| RAIU (median (25-75%)), % | 29.9 (20.9 - 32.6) | 62.9 (55.6 - 72.3) | 0.0018* |
| Thyroid gland weight (median (25-75%)), g | 24.1 (16.9 - 32.2) | 32.7 (23.5 - 42.2) | 0.1396 |
| Dose of 131-I (median (25-75%)), mCi | 13.0 (10.9 - 13.0) | 7.5 (5.5 - 11.9) | 0.0037* |
| Dose of 131-I based on thyroid gland weight (median (25-75%)), μCi/g | 144.8 (121.8 - 176.6) | 156.9 (118.7 - 193.9) | 0.8393 |
| FT4 at RAIT (median (25-75%)), ng/dL | 2.25 (1.79 - 4.02) | 1.47 (0.89 - 1.69) | 0.0034* |
| Difference in FT4 between before drug discontinuation and at RAIT (median (25-75%)), ng/dL | 0.54 (-0.05 - 1.70) | 0.08 (-0.34 - 0.49) | 0.1557 |
| Thyroid function at 1 year after RAIT (R/non-R) | 8:3 | 5:8 | 0.0932 |
| Thyroid gland weight at 1 year after RAIT (median (25-75%)), g | 5.3 (3.2 - 6.4) | 8.9 (6.7 - 12.5) | 0.0065* |
| Dose of drugs at 1 year after RAIT (median (25-75%)), mg | |||
| MMI (n = 0:13) | - | 2.5 (0 - 5) | |
| KI (n = 11:0) | 0 (0-25) | - |