Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access
Article copyright, the authors; Journal compilation copyright, J Endocrinol Metab and Elmer Press Inc
Journal website http://www.jofem.org

Original Article

Volume 9, Number 3, June 2019, pages 37-42


Differences in Clinical and Laboratory Findings Among Graves’ Disease, Painless Thyroiditis and Subacute Thyroiditis Patients With Hyperthyroidism

Tables

Table 1. Clinical Differences Among Patients With Graves’ Disease, Painless Thyroiditis and Subacute Thyroiditis
 
Graves’ diseasePainless thyroiditisSubacute thyroiditis
nValuesnValuesnValues
Values except for sex indicate mean ± SD. *P < 0.001 versus patients with Graves’ disease and painless thyroiditis.
Age (years)6949.0 ± 18.0746.9 ± 21.51053.6 ± 17.3
Sex (female, n (%))6955 (79.7%)75 (71.4%)*103 (30%)*
Body temperature (°C)3536.7 ± 0.4737.0 ± 0.5837.1 ± 0.8
Pulse rate (beats/min)49102.7 ± 17.6691.5 ± 15.1996.0 ± 21.6

 

Table 2. Differences in TSH, Thyroid Hormones and Thyroid Autoantibodies Among Patients With Graves’ Disease, Painless Thyroiditis and Subacute Thyroiditis
 
Graves’ diseasePainless thyroiditisSubacute thyroiditis
nValuesnValuesnValues
Values indicate mean ± SD. Tg-Ab: thyroglobulin antibody; TPO-Ab: thyroid peroxidase antibody; TRAb: TSH receptor antibody; TSH: thyroid-stimulating hormone; T3: triiodothyronine; T4: thyroxine. *P ≤ 0.001 versus patients with Graves’ disease.
TSH (µSH/mL)690.03 ± 0.0170.06 ± 0.09100.03 ± 0.03
Free T3 (pg/mL)6114.0 ± 8.064.5 ± 1.3*98.6 ± 3.3*
Free T4 (µr/dL)693.7 ± 1.971.7 ± 0.4*102.9 ± 0.9
Free T3/Free T4613.6 ± 0.762.7 ± 0.4*93.1 ± 0.8
Third-generation TRAb (IU/L)3716.2 ± 11.950.2 ± 0.3*50.6 ± 0.2*
TPO-Ab (IU/mL)53151.6 ± 199.278.3 ± 3.2*99.7 ± 4.5*
Tg-Ab (IU/mL)51207.4 ± 257.37316.3 ± 196.9914.1 ± 3.4*

 

Table 3. Differences in White Blood Cell Counts and Fractions Among Patients With Graves’ Disease, Painless Thyroiditis and Subacute Thyroiditis
 
Graves’ diseasePainless thyroiditisSubacute thyroiditis
nValuesnValuesnValues
Values indicate mean ± SD. *P < 0.05 versus patients with Graves’ disease.
White blood cells (/µL)665,527.3 ± 1,780.476,385.7 ± 3,913.0109,780.0 ± 4,013.3*
Neutrophils (%)5652.6 ± 12.6664.4 ± 14.6769.3 ± 11.7*
Lymphocytes (%)5636.7 ± 10.8627.2 ± 13.3722.8 ± 11.7*
Monocytes (%)567.7 ± 2.566.3 ± 2.276.6 ± 2.1
Eosinophils (%)562.9 ± 2.661.7 ± 1.571.2 ± 1.2*

 

Table 4. Biochemical Differences Among Patients With Graves’ Disease, Painless Thyroiditis and Subacute Thyroiditis
 
Graves’ diseasePainless thyroiditisSubacute thyroiditis
nValuesnValuesnValues
Values indicate mean ± SD. *P < 0.05 versus patients with Graves’ disease.
Albumin (g/dL)614.1 ± 0.564.2 ± 0.493.7 ± 0.4*
Aspartate transaminase (U/L)6927.3 ± 16.5723.9 ± 7.41025.9 ± 9.1
Alanine aminotransferase (U/L)6934.6 ± 28.0723.0 ± 7.4*1040.0 ± 19.0
Alkaline phosphatase (U/L)57367.2 ± 154.64225.0 ± 56.8*7320.7 ± 108.2
Gamma-glutamyl transpeptidase (U/L)5736.8 ± 34.5330.0 ± 5.3872.6 ± 75.8
Creatine kinase (U/L)5566.4 ± 50.2574.0 ± 26.2973.8 ± 44.9
Total bilirubin (mg/dL)520.7 ± 0.550.6 ± 0.230.6 ± 0.1
Triglyceride (mg/dL)49105.0 ± 57.04105.8 ± 39.97129.4 ± 79.5
High-density lipoprotein cholesterol (mg/dL)4352.9 ± 10.8452.8 ± 8.5743.3 ± 13.6
Low-density lipoprotein cholesterol (mg/dL)4783.3 ± 27.7488.3 ± 17.0781.6 ± 24.4
Blood urea nitrogen (mg/dL)6914.9 ± 5.0712.4 ± 6.1916.1 ± 13.6
Creatinine (mg/dL)690.5 ± 0.270.6 ± 0.2*100.7 ± 0.3
Uric acid (mg/dL)535.3 ± 1.535.7 ± 1.185.5 ± 1.8
Plasma glucose (mg/dL)58114.7 ± 26.95115.0 ± 27.56127.8 ± 21.3
B-type natriuretic peptide (pg/mL)2887.4 ± 109.8461.6 ± 91.1226.1 ± 27.8
C-reactive protein (mg/dL)520.2 ± 0.462.4 ± 4.8104.8 ± 4.0*