J Endocrinol Metab

Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access

Article copyright, the authors; Journal compilation copyright, J Endocrinol Metab and Elmer Press Inc

Journal website http://www.jofem.org

Original Article

Volume 9, Number 4, August 2019, pages 108-112

Food Neophobia in Patients With Phenylketonuria

Figure

Figure 1. Potential factors associated with food neophobia in patients with PKU. Univariate analysis representing the association between patients with PKU and the factors involved with food neophobia. Odds ratios are represented by a log scale with their respective confidence intervals (95%) and statistical significance (P) obtained by Fisher’s exact test. *Values estimated by the likelihood ratio with Agresti correction. PKU: phenylketonuria.

Table

**Table 1.** Demographic and Clinical Characteristics of Patients With Phenylketonuria and Controls
	Patients (n = 25)	Controls (n = 25)	P
Breastfeeding: exclusive up to 6 months of age. Smoking: no patient declared to be a smoker. Food neophobia: self-perception when rejecting new foods. Good metabolic control is defined as a mean Phe level of < 360 µmol/L for patients < 13 years of age or < 600 µmol/L for patients > 13 years of age. PKU: phenylketonuria; F: female; M: male; NS: non-significant; Phe: phenylalanine.
Gender (F/M)	13/12	13/12	NS
Current age (years)	19.3 ± 4.7	19.9 ± 4.9	0.676
Breastfeeding	None	21	< 0.001
Smoking	None	None	NS
Food neophobia	15	4	0.003
Classical/mild PKU	13/12	-	NS
Good metabolic control	10	-	NS