Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access
Article copyright, the authors; Journal compilation copyright, J Endocrinol Metab and Elmer Press Inc
Journal website http://www.jofem.org

Original Article

Volume 2, Number 1, February 2012, pages 39-45


Metabolic Syndrome and Coronary Artery Disease in Indians Younger Than 40 Years

Figures

Figure 1.
Figure 1. Cumulative frequency graph depicting the distribution of number of risk factors in patients with young CAD.
Figure 2.
Figure 2. Cumulative frequency graph depicting the distribution of number of risk factors in young CAD patients with Metabolic Syndrome.

Tables

Table 1. Coronary Risk Factor Profile of Patients With Young CAD
 
Total (n = 246)Male (n = 218)Female (n = 28)P value
NS- not significant.
Age in years (mean ±SD)36.3 ± 4.136.2 ± 4.137.5 ± 3.5NS
Metabolic syndrome66 (26.8%)53 (24.3%)13 (46.4%)< 0.025
Smoking187 (76.0%)177 (81.2%)10 (35.7%)< 0.001
Family History64 (26.0%)54 (24.8%)10 (35.7%)NS
Fasting plasma glucose≥ 100 or previously diagnosed DM54 (21.95%)45 (20.6%)9 (32.1%)NS
Hypertension55 (22.4%)42 (19.3%)13 (46.4%)< 0.005
Reduced HDL cholesterol (< 40 mg/dL in males and < 50 mg/dL in females)171 (69.5%)148 (67.9%)23 (82.1%)NS
Increased Triglycerides (≥ 150 mg/dL)103 (41.9%)92 (42.2%)11 (39.3%)NS
Obesity (≥ 80 cm in females and ≥ 90 cm in males)122 (49.6%)100 (45.9%)22 (78.6%)< 0.005
Waist circumference (cm)87.1 ± 10.587.2 ± 10.686.4 ± 10.1NS
Total cholesterol (mg/dL)171 ± 51.8172.2 ± 53.9165.3 ± 31.1NS
LDL cholesterol (mg/dL)102.5 ± 45.8103.6 ± 47.493.5 ± 30.6NS
HDL cholesterol (mg/dL)36.7 ± 9.336.4 ± 9.238.5 ± 10.5NS
Triglycerides (mg/dL)156 ± 85.7157.2 ± 88.2150 ± 63.7NS

 

Table 2. Coronary Risk Factor Profile of Patients With Metabolic Syndrome and CAD
 
Total (n = 66)Male (n = 53)Female (n = 13)P value
NS- not significant.
Smoking47 (71.1%)42 (79.2%)5 (38.5%)< 0.025
Family History26 (39.4%)18 (34.0%)8 (61.5%)NS
Mean number of components of MS2.61 ± 0.682.57 ± 0.672.77 ± 0.73NS
Fasting plasma glucose ≥ 100 or previously diagnosed DM35 (53.0%)27 (50.9%)8 (61.5%)NS
Hypertension36 (54.5%)26 (49.1%)10 (76.9%)NS
Reduced HDL cholesterol (< 40 mg/dL in males and < 50 mg/dL in females)55 (83.3%)43 (81.1%)12 (92.3%)NS
Increased Triglycerides (≥ 150 mg/dL)49 (74.2%)40 (75.5%)9 (69.2%)NS
Total cholesterol (mg/dL)179 ± 54.5178.8 ± 59.2178.7 ± 29.8NS
LDL cholesterol (mg/dL)102.7 ± 52.1103.8 ± 55.798.2 ± 35.1NS
HDL cholesterol (mg/dL)34.2 ± 8.933.6 ± 8.637 ± 9.97NS
Triglycerides (mg/dL)195 ± 89.8197.6 ± 94.9183.4 ± 67.3NS