Journal of Endocrinology and Metabolism, ISSN 1923-2861 print, 1923-287X online, Open Access
Article copyright, the authors; Journal compilation copyright, J Endocrinol Metab and Elmer Press Inc
Journal website http://www.jofem.org

Letter to the Editor

Volume 2, Number 2, April 2012, pages 102-103

Diagnosis of Hypoglycemia due to Over-Dosage of Insulin Analog, Insulin Lispro

Table

Table 1. Insulin Levels in Patient’s Sera, Premixed Insulin Lispro 75/25, Insulin Lispro and NPH Human Insulin, Measured by Lumipulse Presto Insulin and Insulin Eiken Assay
 
Lumipulse Presto Insulin (CLEIA, µU/ml)Insulin Eiken (RIA, µU/ml)
CLEIA: chemiluminescent enzyme immunoassay; premixed insulin lispro 75/25, 75% insulin lispro protamine suspension and 25% lispro; RIA, radioimmunoassay.
Patient’s sera< 0.333
Insulin lispro mix 75/25
(1 x 10-2 unit)		2.115.2 x 106
Insulin lispro
(1 x 10-2 unit)		< 0.35.4 x 106
NPH human insulin
(1 x 10-2 unit)		2854.3 x 106