Cerebral Venous Sinus Thrombosis in a Patient With Graves’ Disease

Maren Hieber, Johann Lambeck

Abstract


Cerebral venous sinus thrombosis (CVST) constitutes a small proportion of stroke. Its risk factors include hypercoagulability of various causes. We report the case of a 54-year-old woman in whom thrombosis of the left transverse and sigmoid sinus was diagnosed. The extended etiological workup revealed hyperthyroidism, and further analysis showed clinical results consistent with Graves’ disease and decreased levels of protein C. A small number of similar cases - of both the general association of hyperthyroidism and CVST and the additional finding of low protein C - have been described in the literature, so that our case further supports the likely association of hyperthyroidism and hypercoagulability.




J Endocrinol Metab. 2016;6(5):162-164
doi: http://dx.doi.org/10.14740/jem378w


Keywords


Cerebral venous sinus thrombosis; Graves’ disease; Hypercoagulability; Hyperthyroidism; Protein C deficiency

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