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Deficient Activity of Mitochondrial Flavine Adenine Dinucleotide-Linked Glycerophosphate Dehydrogenase in Pancreatic Islet Beta Cells as a Determinant of Non-Insulin-Dependent Diabetes MellitusExtensive experimental investigations in animal models of diabetes mellitus have led to the proposal that a deficient activity of mitochondrial flavine adenine dinucleotide (FAD)-linked glycerophosphate dehydrogenase represents...
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Myelolipomatous Adrenal Adenoma and Adrenal ScintigraphyAdrenal myelolipomas are usually benign and non-functioning masses. On the other hand, adrenal myelolipomatous adenoma that may mimic adrenal myelolipoma on conventional imaging may be a rare cause of subclinical Cushing’s disease.
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Autonomic Diabetic Neuropathy Impairs Glucose and Dipeptidyl Peptidase 4 Inhibitor-Regulated Glucagon Concentration in Type 1 Diabetic Patientsipeptidyl peptidase 4 inhibitors (DPP4i) could exert their glucagonostatic action through a functional autonomic nervous system independently from insulin secretion.
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Olfactory Sulcus Hypoplasia Images of a Case With Kallmann SyndromeKallmann syndrome is a form of hypogonadotropic hypogonadism accompanied by anosmia or hyposmia. MR images of midline defects in Kallmann syndrome were rarely seen in the literature.
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Serologic Screening of Celiac Disease in Patients With Type 1 DiabetesType 1 diabetes mellitus (T1DM) is an autoimmune disorder associated with increased risk of additional autoimmune diseases (ADs) as celiac disease (CD). The aim of this study was to investigate the prevalence of CDs in a population of diabetic children along with the presence of any suggestive clinical signs and symptoms of CD and any effects of CD on the patients’ diabetic control and growth.
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Non-nutritive sweeteners (NNSs) gained attention as dietary tools that provide a free sweet taste of energy to foods. However, its health benefits have been questioned. The aim of this review is to present and discuss the effects of NNSs on energy and glycemic homeostasis, as well as the mechanisms involved. Full Text | Effects of SGLT2 Inhibition on eGFR and Glomerular and Tubular Damage Markers in Japanese Patients With Type 2 Diabetes Sodium-glucose cotransporter 2 (SGLT2) inhibitors are a new class of antihyperglycemic drugs that enhances insulin-independent urinary glucose excretion. Recent studies have suggested that SGLT2 inhibitors possess a renoprotective property in type 2 diabetes patients. However, evidence of the effects of SGLT2 inhibition on glomerular and tubular damage markers is lacking. Full Text | |||
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A Case of Mitochondrial Disease First Diagnosed Over 30 Years After Onset
Mitochondrial disease is induced by mutations in both mitochondrial DNA and DNA of nuclear genes that encode mitochondrial proteins, and there is a general lack of genotype-phenotype correlation in many mitochondrial disorders, which makes the diagnosis of mitochondrial disease difficult. We treated a 37-year-old woman with congenital cataract, bilateral sensory deafness, severe bilateral ptosis, oculomotor disorder in all directions and systemic muscular atrophy and weakness. Full Text
| Current Issue |
Past IssuesVol. 8, No. 6, Dec 2018
Table of Contents
Review
| Non-Nutritive Sweeteners and Their Contradictory Effect on the Control of Energetic and Glycemic Homeostasis | Abstract HTML PDF |
| Ana Paula Souza Silva, Poliana Guiomar Brasiel, Sheila Cristina Potente Dutra Luquetti | 119-125 |
| doi: https://doi.org/10.14740/jem547 |
Original Article
| Add-On Sitagliptin Therapy for Insulin-Treated Type 2 Diabetes: An Analysis of Hemoglobin A1c and Other Variables Using ASSIST-K Follow-Up Data | Abstract HTML PDF |
| Masashi Ishikawa, Masahiko Takai, Hajime Maeda, Akira Kanamori, Akira Kubota, Hikaru Amemiya, Takashi Iizuka, Kotaro Iemitsu, Tomoyuki Iwasaki, Goro Uehara, Shinichi Umezawa, Mitsuo Obana, Hideaki Kaneshige, Mizuki Kaneshiro, Takehiro Kawata, Nobuo Sasai, Tatsuya Saito, Tetsuo Takuma, Hiroshi Takeda, Keiji Tanaka, Shigeru Nakajima, Kazuhiko Hoshino, Shin Honda, Hideo Machimura, Kiyokazu Matoba, Fuyuki Minagawa, Nobuaki Minami, Yukiko Miyairi, Atsuko Mokubo, Tetsuya Motomiya, Manabu Waseda, Masaaki Miyakawa, Yasuo Terauchi, Yasushi Tanaka, Ikuro Matsuba | 126-138 |
| doi: https://doi.org/10.14740/jem540 |
| Iron Supplementation in Non-Anemic Pregnancy and Risk of Developing Gestational Diabetes Mellitus | Abstract HTML PDF |
| Preeyaporn Jirakittidul, Supatra Sirichotiyakul, Chidchanok Ruengorn, Siwaporn Siripenpong, Arinporn Imruetaicharoenchok, Busaba Wiriyasirivaj | 139-143 |
| doi: https://doi.org/10.14740/jem543 |
| Assessment of the Platelet Parameters in Children With Type 1 Diabetes Mellitus | Abstract HTML PDF |
| Ozlem Korkmaz | 144-148 |
| doi: https://doi.org/10.14740/jem537 |
Case Report
| A Case of Mitochondrial Disease First Diagnosed Over 30 Years After Onset | Abstract HTML PDF |
| Ryo Watanabe, Hidekatsu Yanai, Haruka Kamata, Hiroko Yamazaki | 149-152 |
| doi: https://doi.org/10.14740/jem542 |