Journal of Endocrinology and Metabolism

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Frequency: Bimonthly
Journal access: Open Access
ISSN-print: 1923-2861
ISSN-online: 1923-287X
Journal scope: Journal of Endocrinology and Metabolism is an international, open access, peer-reviewed journal. The journal scope encompasses the basic research and clinical research of endocrinology and metabolism. The journal reports the new findings and developments in all endocrine and metabolism fields.
Indexed and covered by: Chemical Abstract (CA); EBSCO; Directory of Open Access Journals (DOAJ);
Worldcat; Google Scholar; Google; JournalTOCs; PubMed: selected citations; Thomson Reuters Emerging Sources Citation Index (ESCI-Web of Science).
Journal archiving and digital preservation: Portico


  • Diabetes Mellitus and the Cardiovascular System

    Diabetes mellitus (DM) is an epidemic which affects close to 100 million patients worldwide; the majority being type 2 diabetes mellitus. The rising incidence has resulted in a proportional increase in the frequency of cardiovascular disease attributable to DM, as revealed by various population-based studies.

  • Global Gene Expression Profiling in Omental Adipose Tissue of Morbidly Obese Diabetic African Americans

    Adipose tissues play an important role in the pathophysiology of obesity-related diseases including type 2 diabetes (T2D).

  • Myelolipomatous Adrenal Adenoma and Adrenal Scintigraphy

    Adrenal myelolipomas are usually benign and non-functioning masses. On the other hand, adrenal myelolipomatous adenoma that may mimic adrenal myelolipoma on conventional imaging may be a rare cause of subclinical Cushing’s disease.

  • Autonomic Diabetic Neuropathy Impairs Glucose and Dipeptidyl Peptidase 4 Inhibitor-Regulated Glucagon Concentration in Type 1 Diabetic Patients

    ipeptidyl peptidase 4 inhibitors (DPP4i) could exert their glucagonostatic action through a functional autonomic nervous system independently from insulin secretion.

  • Olfactory Sulcus Hypoplasia Images of a Case With Kallmann Syndrome

    Kallmann syndrome is a form of hypogonadotropic hypogonadism accompanied by anosmia or hyposmia. MR images of midline defects in Kallmann syndrome were rarely seen in the literature.







Harnessing Structural Data of Insulin and Insulin Receptor for Therapeutic Designs

To lower blood glucose concentration, insulin binds to insulin receptor (IR) that possesses two distinct insulin binding sites to trigger downstream signaling events leading to an increased uptake of glucose into muscle and fat cells. Comprehensive understandings of structural and dynamic mechanisms of insulin and its receptor are essential to design therapeutic agents for treating and delaying the onset of diabetes that affects over 347 million people worldwide. Full Text

Beneficial Effects of Incretin-Based Therapy on Glycemic Control, Adipokines, Insulin Sensitivity Parameters and Weight Loss in Overweight or Obese Patients With Newly Diagnosed Type 2 Diabetes: A Prospective Study

The aim of the study was to examine the incretin-based therapy on glycemic control, insulin sensitivity parameters, weight loss and adipokines in overweight or obese patients with newly diagnosed type 2 diabetes mellitus (T2DM). Full Text

Image of the Issue

Ipilimumab-Induced Hypophysitis May Not Affect All Pituitary Cell Lines: A Case Report
Hypophysitis, a rare autoimmune condition, has now emerged as an adverse effect of ipilimumab (anti-cytotoxic T lymphocyte antigen 4 (CTLA4) mAb) therapy. The occurrence of ipilimumab-induced hypophysitis (IH) in studies has varied from 0% to 17%. This condition, because of secondary adrenal insufficiency, may be life-threatening if not recognized and managed promptly. Here we present a case of hypophysitis in the setting of ipilimumab therapy for malignant melanoma. Full Text

Current Issue

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Vol. 5, No. 6, Dec 2015

Table of Contents


Diabetes Mellitus and the Cardiovascular System Abstract HTML PDF
Pavani Kolakalapudi, Bassam Omar 313-320

Original Article

Observational Study of Patients in Morocco With Uncontrolled Type 2 Diabetes Treated With Metformin and/or Sulfonylurea With or Without Insulin Abstract HTML PDF
Nawal El Ansari, Asmae Chadli, Siham El Aziz, Ghizlane El Mghari, Youness El Achhab, Mehdi Seqat, Chakib Nejjari 321-327
Epidemiological Trends in the Morbidity and Mortality Among Adults With Type 2 Diabetes Mellitus in South Korea Between 2009 and 2012 Abstract HTML PDF
Young-Han Kwon, Hyeong-Ae Bang, Won-Hak Kim, Myeong-Jin Lee, Won-Chang Lee 328-332
Observational Study of the Use of Insulin Glargine as Basal Therapy in Patients With Type 2 Diabetes Mellitus in Morocco Abstract HTML PDF
Abdelmjid Chraibi, Hinde Iraqi, Mehdi Seqat, Youness El Achhab, Chakib Nejjari 333-336

Case Report

Cyclophosphamide-Induced Hyponatremia in a Patient With Diabetes Insipidus Abstract HTML PDF
Rachel A. Steinman, Sara E. Schwab, Kashif M. Munir 337-339
A Natural Fermented Food as a Possible Cause of Syndrome of Inappropriate Secretion of Antidiuretic Hormone Abstract HTML PDF
Hidetaka Hamasaki 340-341
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Journal of Endocrinology and Metabolism, bimonthly, ISSN 1923-2861 (print), 1923-287X (online), published by Elmer Press Inc.     
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